分離済み変異体

tm1605

Allele Nametm1605
BalanceNot Required
OutCrossNot Accepted
Sequence NameK11E8.1
Gene Nameunc-43
Worm BaseAllele Name tm1605
Gene Name unc-43
Sequence K11E8.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 15890/15891-16541/16542 (651 bp deletion)
ChromosomeIV
Putative gene structurecomplement((join(AL023841.1:237..295, 16829..17038, 16713..16778, 16342..16414, 15970..16153, 15827..15921, 15653..15775, 15488..15571, 11979..12025, 9611..9729, 6952..7050, 5457..5570, 4424..4499, 4129..4220, 3825..3933, 2851..2980))
Map position4.57
Balancer
Map position of balancer
Sequence of primersExtFwd:GCAGTCAACAGTATCCTGTC,IntFwd:GGATAGCTGATGCAACGCGT,ExtRev:ATAACTCGCGCGAGGCAGAG,IntRev:TGGGAAAGATGCTCACGTAC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Roussos A, Kitopoulou K, Borbolis F, Ploumi C, Gianniou DD, Li Z, He H, Tsakiri E, Borland H, Kostakis IK, Samiotaki M, Trougakos IP, Bohr VA, Palikaras K.
Urolithin Α modulates inter-organellar communication via calcium-dependent mitophagy to promote healthy ageing.
Autophagy 2025 21(12) 3097-3122 
[ PubMed ID = 40944367 ] [ RRC reference ]

Petratou D, Gjikolaj M, Kaulich E, Schafer W, Tavernarakis N.
A proton-inhibited DEG/ENaC ion channel maintains neuronal ionstasis and promotes neuronal survival under stress.
iScience 2023 26(7) 107117 
[ PubMed ID = 37416472 ] [ RRC reference ]