Home > 分離済み変異体 > tm1599

分離済み変異体

Allele Name		tm1599
Balance		Completed
OutCross		Not Accepted
Sequence Name		F22D6.6
Gene Name		ekl-1
Worm Base	Allele Name	tm1599 (x1)
	Gene Name	ekl-1
	Sequence	F22D6.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		lethal or sterile
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		21872/21873-22625/22626 (753 bp deletion)
Chromosome		I
Putative gene structure		join(22130..22261, 22319..22440, 22482..22746, 22821..23311, 23361..23465, 23516..23692, 23738..23926, 24213..24277, 24325..24411, 24458..24543, 24621..24722)
Map position		1.73
Balancer		hT2 [bli-4(e937) let-? qIs48]
Map position of balancer
Sequence of primers		ExtRev:GGTGTGCAGTAACTTACCTG,IntRev:CATCGGTGGGAACCGGCAAT,ExtFwd:GTCAAGTGTAACGCGCCAGT,IntFwd:ACGCGCCAGTAGTCGGTTCT
Distributed lab
Depositor		Dr. S. Mitani
References		Please submit your publication Furuta T, Arur S. sart-3 functions to regulate germline sex determination in C. elegans . MicroPubl Biol 2023 2023   [ PubMed ID = 37206989 ] [ RRC reference ] Davis GM, Tu S, Anderson JW, Colson RN, Gunzburg MJ, Francisco MA, Ray D, Shrubsole SP, Sobotka JA, Seroussi U, Lao RX, Maity T, Wu MZ, McJunkin K, Morris QD, Hughes TR, Wilce JA, Claycomb JM, Weng Z, Boag PR. The TRIM-NHL protein NHL-2 is a co-factor in the nuclear and somatic RNAi pathways in C. elegans. Elife 2018 7   [ PubMed ID = 30575518 ] [ RRC reference ] Maniar JM, Fire AZ. EGO-1, a C. elegans RdRP, modulates gene expression via production of mRNA-templated short antisense RNAs. Curr Biol 2011 21(6) 449-59  [ PubMed ID = 21396820 ] [ RRC reference ] Claycomb JM, Batista PJ, Pang KM, Gu W, Vasale JJ, van Wolfswinkel JC, Chaves DA, Shirayama M, Mitani S, Ketting RF, Conte D Jr, Mello CC. The Argonaute CSR-1 and its 22G-RNA cofactors are required for holocentric chromosome segregation. Cell 2009 139(1) 123-34  [ PubMed ID = 19804758 ] [ RRC reference ]