分離済み変異体

tm1597

Allele Nametm1597
BalanceNot Required
OutCrossNot Accepted
Sequence NameC41C4.6
Gene Nameulp-4
Worm BaseAllele Name tm1597
Gene Name ulp-4
Sequence C41C4.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" Homozygous viable. Dr. J. Ahringer: low percentage embryonic lethality and pvl (might be from side mutation). Dr. W. Vermeulen: not sensitive to UV-irradiation. Dr. J. Kaplan: wt locomotion and aldicarb sensitivity.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 30098/30099-30502/30503 (404 bp deletion)
ChromosomeII
Putative gene structurejoin(30537..30684, 30734..30915, 31080..31181, 32818..33366, 34782..34829)
Map position0.71
Balancer
Map position of balancer
Sequence of primersIntRev:GGCGCGCTGCCATAAGATCT,ExtRev:TGGCACCGAACACCCTCCTA,IntFwd:TCCGTCGATCTAAATAGCAG,ExtFwd:CCAATCATGTGATTGCACCT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Alexander KD, Ramachandran S, Biswas K, Lambert CM, Russell J, Oliver DB, Armstrong W, Rettler M, Liu S, Doitsidou M, Bénard C, Walker AK, Francis MM.
The homeodomain transcriptional regulator DVE-1 directs a program for synapse elimination during circuit remodeling.
Nat Commun 2023 14(1) 7520 
[ PubMed ID = 37980357 ] [ RRC reference ]

Gao K, Li Y, Hu S, Liu Y.
SUMO peptidase ULP-4 regulates mitochondrial UPR-mediated innate immunity and lifespan extension.
Elife 2019 8  
[ PubMed ID = 30642431 ] [ RRC reference ]