Home > 分離済み変異体 > tm1583

分離済み変異体

Allele Name		tm1583
Balance		Not Required
OutCross		Not Accepted
Sequence Name		C10C6.2
Gene Name		npr-3
Worm Base	Allele Name	tm1583
	Gene Name	npr-3
	Sequence	C10C6.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		23997/23998-TTTT-25814/25815 (1817 bp deletion + 4 bp insertion)
Chromosome		IV
Putative gene structure		join(24241..24402,24873..25025,25145..25228,25787..25923, 26058..26273, 26935..27226, 27272..27358)
Map position		4.99
Balancer
Map position of balancer
Sequence of primers		ExtFwd:TCTAAGAGAGAAGGCTCGCT,IntFwd:GTCAGCTCTAACTAGGGTAC,ExtRev:CCGGATTGAAATCAGGCCTG,IntRev:TCGTATACTGCAATGTCGCT
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Otarigho B, Butts AF, Aballay A. Neuronal NPR-15 modulates molecular and behavioral immune responses via the amphid sensory neuron-intestinal axis in C. elegans. Elife 2024 12   [ PubMed ID = 38446031 ] [ RRC reference ] Chai CM, Park H, Sternberg PW. Brain-wide bidirectional neuropeptide modulation of individual neuron classes regulates a developmental decision. Curr Biol 2022 32(15) 3365-3373.e6  [ PubMed ID = 35679871 ] [ RRC reference ] Chew YL, Tanizawa Y, Cho Y, Zhao B, Yu AJ, Ardiel EL, Rabinowitch I, Bai J, Rankin CH, Lu H, Beets I, Schafer WR. An Afferent Neuropeptide System Transmits Mechanosensory Signals Triggering Sensitization and Arousal in C. elegans. Neuron 2018 99(6) 1233-1246.e6  [ PubMed ID = 30146306 ] [ RRC reference ] Luo J, Xu Z, Tan Z, Zhang Z, Ma L. Neuropeptide receptors NPR-1 and NPR-2 regulate Caenorhabditis elegans avoidance response to the plant stress hormone methyl salicylate. Genetics 2015 199(2) 523-31  [ PubMed ID = 25527285 ] [ RRC reference ] Yemini E, Jucikas T, Grundy LJ, Brown AE, Schafer WR. A database of Caenorhabditis elegans behavioral phenotypes. Nat Methods 2013 10(9) 877-9  [ PubMed ID = 23852451 ] [ RRC reference ] Hapiak V, Summers P, Ortega A, Law WJ, Stein A, Komuniecki R. Neuropeptides amplify and focus the monoaminergic inhibition of nociception in Caenorhabditis elegans. J Neurosci 2013 33(35) 14107-16  [ PubMed ID = 23986246 ] [ RRC reference ] Cohen M, Reale V, Olofsson B, Knights A, Evans P, de Bono M. Coordinated regulation of foraging and metabolism in C. elegans by RFamide neuropeptide signaling. Cell Metab 2009 9(4) 375-85  [ PubMed ID = 19356718 ] [ RRC reference ]