分離済み変異体

tm1575

Allele Nametm1575
Allele Type通常株
Sequence NameF31E3.4
Gene Namepanl-2
Worm BaseAllele Name tm1575
Gene Name panl-2
Sequence F31E3.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" Homozygous viable. Dr. D. Greenstein: responds to RNAi.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 4090/4091-AAACT-5035/5036 (945 bp deletion + 5 bp insertion)
ChromosomeIII
Putative gene structurecomplement(join(1435..1673, 1738..1831, 1877..2030, 2078..2229, 2301..2865, 2915..3129, 3175..3383, 3440..4050, 4095..4219, 4279..4358, 4404..4720, 4767..4885, 4937..5141, 5188..5360, 5412..5516, 5567..5599))
Map position-0.87
Balancer
Map position of balancer
Sequence of primersIntFwd:ACCTGTTCGAGCGACATCAT,ExtFwd:ATCGGAGATGACGATCGAAC,IntRev:TGGCGATTTGTGGCGCCGAT,ExtRev:TAAACATGGCGTCGGCAACT
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Nousch M, Yeroslaviz A, Eckmann CR.
Stage-specific combinations of opposing poly(A) modifying enzymes guide gene expression during early oogenesis.
Nucleic Acids Res 2019 47(20) 10881-10893 
[ PubMed ID = 31511882 ] [ RRC reference ]

Nousch M, Techritz N, Hampel D, Millonigg S, Eckmann CR.
The Ccr4-Not deadenylase complex constitutes the main poly(A) removal activity in C. elegans.
J Cell Sci 2013 126(Pt 18) 4274-85 
[ PubMed ID = 23843623 ] [ RRC reference ]