Home > 分離済み変異体 > tm1574

分離済み変異体

Allele Name		tm1574
Balance		Not Required
OutCross		Not Accepted
Sequence Name		F15C11.2
Gene Name		ubql-1
Worm Base	Allele Name	tm1574
	Gene Name	ubql-1
	Sequence	F15C11.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		[VF15C11L] 1079/1080-[VF15C11L] 1834/1835 (755 bp deletion)
Chromosome		I
Putative gene structure		join(Z98262.1[VF15C11L]:1264..1356, Z98262.1:1479..1584, Z98262.1:1630..1937, Z98262.1:2046..2174, Z98262.1:2739..2980, 105..106, 433..572, 618..701, 748..860, 908..973, 1018..1078, 4969..5071, 5120..5181)
Map position		1.65
Balancer
Map position of balancer
Sequence of primers		IntRev:CTATTGAGCAAGGGCTCCTG,ExtRev:GTCCAGCACGATCGACACGT,ExtFwd:ACGTGGCGCTCGTGTGTACA,IntFwd:CCAGGGATTGGTAGGAACTG
Distributed lab
Depositor		Dr. S. Mitani
References		Please submit your publication Erinjeri AP, Wang X, Williams R, Chiozzi RZ, Thalassinos K, Labbadia J. HSF-1 promotes longevity through ubiquilin-1-dependent mitochondrial network remodelling. Nat Commun 2024 15(1) 9797  [ PubMed ID = 39532882 ] [ RRC reference ] Eck RJ, Stair JG, Kraemer BC, Liachko NF. Simple models to understand complex disease: 10 years of progress from Caenorhabditis elegans models of amyotrophic lateral sclerosis and frontotemporal lobar degeneration. Front Neurosci 2023 17 1300705  [ PubMed ID = 38239833 ] [ RRC reference ] Osborne JF, Yanagi KS, Hart AC. Genetic interactions in a C. elegans sod-1 ALS model: glutamatergic neuron degeneration. MicroPubl Biol 2021 2021   [ PubMed ID = 33474528 ] [ RRC reference ] Jablonski AM, Lamitina T, Liachko NF, Sabatella M, Lu J, Zhang L, Ostrow LW, Gupta P, Wu CY, Doshi S, Mojsilovic-Petrovic J, Lans H, Wang J, Kraemer B, Kalb RG. Loss of RAD-23 Protects Against Models of Motor Neuron Disease by Enhancing Mutant Protein Clearance. J Neurosci 2015 35(42) 14286-306  [ PubMed ID = 26490867 ] [ RRC reference ]