分離済み変異体

tm1568

Allele Nametm1568
BalanceNot Required
OutCrossNot Accepted
Sequence NameC53C7.1
Gene Namenpr-10
Worm BaseAllele Name tm1568
Gene Name npr-10
Sequence C53C7.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. H. R. Horvitz: WT for gross morphology, locomotion and growth rate.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 2465/2466-3039/3040 (574 bp deletion)
ChromosomeX
Putative gene structurecomplement(join(608..697, 754..868, 1147..1277, 1849..2033, 2087..2256, 2303..2385, 2612..2816, 3633..3751))
Map position9.67
Balancer
Map position of balancer
Sequence of primersExtFwd:CCGGGAAGCGCTGAGTAATC,IntFwd:AGCCAACAGATGGCAGCCAT,ExtRev:ATTGCGGTAAGAGTGGGGTG,IntRev:GTGTACCACCAGATGAGTAA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Otarigho B, Butts AF, Aballay A.
Neuronal NPR-15 modulates molecular and behavioral immune responses via the amphid sensory neuron-intestinal axis in C. elegans.
Elife 2024 12  
[ PubMed ID = 38446031 ] [ RRC reference ]

Chew YL, Tanizawa Y, Cho Y, Zhao B, Yu AJ, Ardiel EL, Rabinowitch I, Bai J, Rankin CH, Lu H, Beets I, Schafer WR.
An Afferent Neuropeptide System Transmits Mechanosensory Signals Triggering Sensitization and Arousal in C. elegans.
Neuron 2018 99(6) 1233-1246.e6 
[ PubMed ID = 30146306 ] [ RRC reference ]

Yemini E, Jucikas T, Grundy LJ, Brown AE, Schafer WR.
A database of Caenorhabditis elegans behavioral phenotypes.
Nat Methods 2013 10(9) 877-9 
[ PubMed ID = 23852451 ] [ RRC reference ]

Hapiak V, Summers P, Ortega A, Law WJ, Stein A, Komuniecki R.
Neuropeptides amplify and focus the monoaminergic inhibition of nociception in Caenorhabditis elegans.
J Neurosci 2013 33(35) 14107-16 
[ PubMed ID = 23986246 ] [ RRC reference ]