分離済み変異体

tm1553

Allele Name

tm1553

Balance

Not Required

OutCross

Not Accepted

Sequence Name

C56G3.1

Gene Name

npr-8

Worm Base

Allele Name

tm1553

Gene Name

npr-8

Sequence

C56G3.1

Phenotype

homozygous viable. Dr. L. Avery: feeding and satiety behavior normal.

Mutation site

22624/22625-22923/22924 (299 bp deletion)

Chromosome

Putative gene structure

join(22556..22651, 22702..22896, 22955..23106, 23448..23598, 23696..24178, 24285..24496, 24544..24630, 24706..24802)

Map position

-1.75

Balancer

Map position of balancer

Sequence of primers

ExtFwd:GGCAACCGGGATTTGCGTAG,IntFwd:GCTCTTTTTGGTGGGAGGGA,ExtRev:CATGATGGAATCGGCCGGCT,IntRev:GCGAATGTATCGGTAGTAGA

Distributed lab

Depositor

Dr. S. Mitani/NBRP

References

Please submit your publication

Otarigho B, Butts AF, Aballay A.
Neuronal NPR-15 modulates molecular and behavioral immune responses via the amphid sensory neuron-intestinal axis in C. elegans.
Elife 2024 12
[ PubMed ID = 38446031 ] [ RRC reference ]

Chew YL, Tanizawa Y, Cho Y, Zhao B, Yu AJ, Ardiel EL, Rabinowitch I, Bai J, Rankin CH, Lu H, Beets I, Schafer WR.
An Afferent Neuropeptide System Transmits Mechanosensory Signals Triggering Sensitization and Arousal in C. elegans.
Neuron 2018 99(6) 1233-1246.e6
[ PubMed ID = 30146306 ] [ RRC reference ]

Yemini E, Jucikas T, Grundy LJ, Brown AE, Schafer WR.
A database of Caenorhabditis elegans behavioral phenotypes.
Nat Methods 2013 10(9) 877-9
[ PubMed ID = 23852451 ] [ RRC reference ]

Hapiak V, Summers P, Ortega A, Law WJ, Stein A, Komuniecki R.
Neuropeptides amplify and focus the monoaminergic inhibition of nociception in Caenorhabditis elegans.
J Neurosci 2013 33(35) 14107-16
[ PubMed ID = 23986246 ] [ RRC reference ]

Cohen M, Reale V, Olofsson B, Knights A, Evans P, de Bono M.
Coordinated regulation of foraging and metabolism in C. elegans by RFamide neuropeptide signaling.
Cell Metab 2009 9(4) 375-85
[ PubMed ID = 19356718 ] [ RRC reference ]