分離済み変異体

tm1521

Allele Nametm1521
Allele Type通常株
Sequence NameR05G6.8
Gene Nameplc-4
Worm BaseAllele Name tm1521
Gene Name plc-4
Sequence R05G6.8
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. E. Jorgensen: defacation cycle normal. Dr. I. Mori: SBN-1::Venus in RIA neurons could not be observed.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 9765/9766-11003/11004 (1238 bp deletion)
ChromosomeIV
Putative gene structurecomplement(join(8350..8514, 8564..9108, 9153..9516, 9848..9945, 9996..10296, 10343..10729, 10891..11170, 11218..11333))
Map position3.34
Balancer
Map position of balancer
Sequence of primersIntRev:TGGCCCATGCCCGCATCTTT,IntFwd:CGAGGGTGAGGATGACAGGA,ExtFwd:CGACGTGGTTTTCGAGGGTG,ExtRev:GATAACGGAGCATCGTACCT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Tsai Y, Lin YC, Lee YH.
Octopamine-MAPK-SKN-1 signaling suppresses mating-induced oxidative stress in Caenorhabditis elegans gonads to protect fertility.
iScience 2023 26(3) 106162 
[ PubMed ID = 36876134 ] [ RRC reference ]

Vázquez-Manrique RP, Legg JC, Olofsson B, Ly S, Baylis HA.
Improved gene targeting in C. elegans using counter-selection and Flp-mediated marker excision.
Genomics 2010 95(1) 37-46 
[ PubMed ID = 19747540 ] [ RRC reference ]