Home > 分離済み変異体 > tm1512

分離済み変異体

Allele Name		tm1512
Balance		Not Required
OutCross		Not Accepted
Sequence Name		Y39A1A.5
Gene Name		rabx-5
Worm Base	Allele Name	tm1512
	Gene Name	rabx-5
	Sequence	Y39A1A.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr. Y. Jin: normal behavior. Dr. B. Grant: Nature Cell Biol. 7, 559-569 (2005).
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		8810/8811-9793/9794 (983 bp deletion)
Chromosome		III
Putative gene structure		join(8497..8559, 9470..9553, 9733..9848, 10170..10270, 10365..10416, 14130..14677, 15303..15440, 15752..16004, 16352..16433, 16754..16954)
Map position		3.91
Balancer
Map position of balancer
Sequence of primers		ExtFwd:GCGCGGCAGATGTTCTGTGT,IntFwd:ATTCCCCCAGATTGTGTATG,ExtRev:CCGGTGACGTGGAAGTTGGT,IntRev:TTGGTGAACTGGTTCCGCCT
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Sann SB, Crane MM, Lu H, Jin Y. Rabx-5 regulates RAB-5 early endosomal compartments and synaptic vesicles in C. elegans. PLoS One 2012 7(6) e37930  [ PubMed ID = 22675499 ] [ RRC reference ] Dwivedi M, Sung H, Shen H, Park BJ, Lee S. Disruption of endocytic pathway regulatory genes activates autophagy in C. elegans. Mol Cells 2011 31(5) 477-81  [ PubMed ID = 21618079 ] [ RRC reference ] Audhya A, Desai A, Oegema K. A role for Rab5 in structuring the endoplasmic reticulum. J Cell Biol 2007 178(1) 43-56  [ PubMed ID = 17591921 ] [ RRC reference ] Sato M, Sato K, Fonarev P, Huang CJ, Liou W, Grant BD. Caenorhabditis elegans RME-6 is a novel regulator of RAB-5 at the clathrin-coated pit. Nat Cell Biol 2005 7(6) 559-69  [ PubMed ID = 15895077 ] [ RRC reference ]