Home > 分離済み変異体 > tm1497

分離済み変異体

Allele Name		tm1497
Balance		Not Required
OutCross		Not Accepted
Sequence Name		F41E7.3
Gene Name		npr-6
Worm Base	Allele Name	tm1497
	Gene Name	npr-6
	Sequence	F41E7.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr. O. Hobert: no defects in thermotaxis. Dr. C. Bargmann: viable, fertile, normal locomotion.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		8809/8810-9715/9716 (906 bp deletion)
Chromosome		X
Putative gene structure		complement(join(6923..7017, 7175..7258, 7307..7380, 7872..8009, 8057..8232, 8321..8497, 8717..8829, 8887..8972, 9022..9116, 9168..9254, 9384..9467))
Map position		1.84
Balancer
Map position of balancer
Sequence of primers		ExtRev:CGCGTCTAGAATTGCAAGTC,IntRev:TGAGGGAAGTGTTTGGCTCA,ExtFwd:GCGGTAGCTGTCATACTCAT,IntFwd:GCCACGCATGAAATTATCCA
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Marquina-Solis J, Feng L, Vandewyer E, Beets I, Hawk J, Colón-Ramos DA, Yu J, Fox BW, Schroeder FC, Bargmann CI. Antagonism between neuropeptides and monoamines in a distributed circuit for pathogen avoidance. Cell Rep 2024 43(4) 114042  [ PubMed ID = 38573858 ] [ RRC reference ] Otarigho B, Butts AF, Aballay A. Neuronal NPR-15 modulates molecular and behavioral immune responses via the amphid sensory neuron-intestinal axis in C. elegans. Elife 2024 12   [ PubMed ID = 38446031 ] [ RRC reference ] Ji H, Fouad AD, Li Z, Ruba A, Fang-Yen C. A proprioceptive feedback circuit drives Caenorhabditis elegans locomotor adaptation through dopamine signaling. Proc Natl Acad Sci U S A 2023 120(20) e2219341120  [ PubMed ID = 37155851 ] [ RRC reference ] Hapiak V, Summers P, Ortega A, Law WJ, Stein A, Komuniecki R. Neuropeptides amplify and focus the monoaminergic inhibition of nociception in Caenorhabditis elegans. J Neurosci 2013 33(35) 14107-16  [ PubMed ID = 23986246 ] [ RRC reference ] Cohen M, Reale V, Olofsson B, Knights A, Evans P, de Bono M. Coordinated regulation of foraging and metabolism in C. elegans by RFamide neuropeptide signaling. Cell Metab 2009 9(4) 375-85  [ PubMed ID = 19356718 ] [ RRC reference ]