Home > 分離済み変異体 > tm1496

分離済み変異体

Allele Name		tm1496
Balance		Completed
OutCross		Not Accepted
Sequence Name		T23G7.5
Gene Name		pir-1
Worm Base	Allele Name	tm1496 (x1)
	Gene Name	pir-1
	Sequence	T23G7.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		lethal or sterile. Dr. C. Mello, Cell 124, 343-354 (2006)
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		12300/12301-13009/13010 (709 bp deletion)
Chromosome		II
Putative gene structure		join(12488..12654, 12851..13093, 13144..13241, 13297..13407, 13455..13621)
Map position		1.02
Balancer		mIn1 [e128 mIs14]
Map position of balancer
Sequence of primers		ExtFwd:CATCTACCCAGACTGCGGAT,IntFwd:CTATTCGTACTTCACCGGGA,ExtRev:CACTCCAACCGTCTCTCCAC,IntRev:ATCGGCTGAGTTTCCGCTGC
Distributed lab
Depositor		Dr. S. Mitani
References		Please submit your publication Chaves DA, Dai H, Li L, Moresco JJ, Oh ME, Conte D Jr, Yates JR 3rd, Mello CC, Gu W. The RNA phosphatase PIR-1 regulates endogenous small RNA pathways in C. elegans. Mol Cell 2021 81(3) 546-557.e5  [ PubMed ID = 33378643 ] [ RRC reference ] Nakagawa A, Shi Y, Kage-Nakadai E, Mitani S, Xue D. Caspase-dependent conversion of Dicer ribonuclease into a death-promoting deoxyribonuclease. Science 2010 328(5976) 327-34  [ PubMed ID = 20223951 ] [ RRC reference ] Duchaine TF, Wohlschlegel JA, Kennedy S, Bei Y, Conte D Jr, Pang K, Brownell DR, Harding S, Mitani S, Ruvkun G, Yates JR 3rd, Mello CC. Functional proteomics reveals the biochemical niche of C. elegans DCR-1 in multiple small-RNA-mediated pathways. Cell 2006 124(2) 343-54  [ PubMed ID = 16439208 ] [ RRC reference ]