Home > 分離済み変異体 > tm1483

分離済み変異体

Allele Name		tm1483
Balance		Completed
OutCross		Not Accepted
Sequence Name		F17C11.8
Gene Name		vps-36
Worm Base	Allele Name	tm1483 (x1)
	Gene Name	vps-36
	Sequence	F17C11.8
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		lethal or sterile. Dr. G. Hermann: wild-type gut granules. Dr. M. Zhen: L3 or L4 lethal in homozygous animals. No obvious defects in nervous system.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		25565/25566-GATTTGATTTTTGAACTTTTTGAACGATTAACGATTTTTGAACGATTA-26180/26181 (615 bp deletion + 48 bp insertion)
Chromosome		V
Putative gene structure		complement(join(24870..24957, 25008..25645, 25694..25768, 25886..26140, 26283..26387, 26526..26657))
Map position		2.84
Balancer		nT1 [qIs51]
Map position of balancer
Sequence of primers		ExtFwd:CGAGTACTCCAGAAGGGAAT,IntFwd:GACTTAGTGCCCCGCATGCA,ExtRev:CGTGTCATTGTGCCACCTAA,IntRev:GAGTATGTGCTGCAAGCCTA
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Lefebvre C, Largeau C, Michelet X, Fourrage C, Maniere X, Matic I, Legouis R, Culetto E. The ESCRT-II proteins are involved in shaping the sarcoplasmic reticulum in C. elegans. J Cell Sci 2016 129(7) 1490-9  [ PubMed ID = 26906413 ] [ RRC reference ] Djeddi A, Michelet X, Culetto E, Alberti A, Barois N, Legouis R. Induction of autophagy in ESCRT mutants is an adaptive response for cell survival in C. elegans. J Cell Sci 2012 125(Pt 3) 685-94  [ PubMed ID = 22389403 ] [ RRC reference ] Roudier N, Lefebvre C, Legouis R. CeVPS-27 is an endosomal protein required for the molting and the endocytic trafficking of the low-density lipoprotein receptor-related protein 1 in Caenorhabditis elegans. Traffic 2005 6(8) 695-705  [ PubMed ID = 15998324 ] [ RRC reference ]