分離済み変異体

tm1453

Allele Nametm1453
BalanceNot Required
OutCrossNot Accepted
Sequence NameT05F1.1
Gene Namedhs-4
Worm BaseAllele Name tm1453
Gene Name dhs-4
Sequence T05F1.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 1096/1097-TTGATAAA-1530/1531 (434 bp deletion + 8 bp insertion)
ChromosomeI
Putative gene structurejoin(64..141, 187..338, 386..512, 571..1114, 1166..1289, 1339..1921, 1971..2036)
Map position3.83
Balancer
Map position of balancer
Sequence of primersIntRev:GCGAGTGGGTAGCAATCTGT,ExtRev:CCCTCGATAGTGTTCTGCGA,IntFwd:GAGTTTCATGCGTACCGTCT,ExtFwd:TTTAGGTGAACGGGTCCCAG
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Richard M, Boulin T, Robert VJ, Richmond JE, Bessereau JL.
Biosynthesis of ionotropic acetylcholine receptors requires the evolutionarily conserved ER membrane complex.
Proc Natl Acad Sci U S A 2013 110(11) E1055-63 
[ PubMed ID = 23431131 ] [ RRC reference ]

Almedom RB, Liewald JF, Hernando G, Schultheis C, Rayes D, Pan J, Schedletzky T, Hutter H, Bouzat C, Gottschalk A.
An ER-resident membrane protein complex regulates nicotinic acetylcholine receptor subunit composition at the synapse.
EMBO J 2009 28(17) 2636-49 
[ PubMed ID = 19609303 ] [ RRC reference ]

Gottschalk A, Almedom RB, Schedletzky T, Anderson SD, Yates JR 3rd, Schafer WR.
Identification and characterization of novel nicotinic receptor-associated proteins in Caenorhabditis elegans.
EMBO J 2005 24(14) 2566-78 
[ PubMed ID = 15990870 ] [ RRC reference ]