分離済み変異体

tm1449

Allele Nametm1449
BalanceNot Required
OutCrossNot Accepted
Sequence NameB0024.6
Gene Namegcy-6
Worm BaseAllele Name tm1449
Gene Name gcy-6
Sequence B0024.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. Y-K. Paik: dauer formed on daumone plate. Dr. O. Hobert: Mg chemotaxis defective.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 26845/26846-27031/27302 (456 bp deletion)
ChromosomeV
Putative gene structurecomplement(join(21722..21805, 21856..22100, 23485..24088, 24131..24219, 24264..24413, 24494..24815, 24853..25147, 25195..25528, 25611..25746, 25794..25913, 25963..26075, 26122..26253, 26301..26527, 26703..26835, 26888..26997, 27162..27271, 27312..27526, 27733..27799))
Map position2.47
Balancer
Map position of balancer
Sequence of primersExtRev:TTCGGGCATCGGTAGACAGA,IntRev:TCGGTAGACAGATAACCTGA,ExtFwd:CGCGCACGCATCTGTACAAT,IntFwd:GGGCCTGTAGCTTCAGTCCA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Murayama T, Takayama J, Fujiwara M, Maruyama IN.
Environmental alkalinity sensing mediated by the transmembrane guanylyl cyclase GCY-14 in C. elegans.
Curr Biol 2013 23(11) 1007-12 
[ PubMed ID = 23664973 ] [ RRC reference ]

Mok CA, Healey MP, Shekhar T, Leroux MR, Héon E, Zhen M.
Mutations in a guanylate cyclase GCY-35/GCY-36 modify Bardet-Biedl syndrome-associated phenotypes in Caenorhabditis elegans.
PLoS Genet 2011 7(10) e1002335 
[ PubMed ID = 22022287 ] [ RRC reference ]

Hallem EA, Spencer WC, McWhirter RD, Zeller G, Henz SR, Rätsch G, Miller DM 3rd, Horvitz HR, Sternberg PW, Ringstad N.
Receptor-type guanylate cyclase is required for carbon dioxide sensation by Caenorhabditis elegans.
Proc Natl Acad Sci U S A 2011 108(1) 254-9 
[ PubMed ID = 21173231 ] [ RRC reference ]