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分離済み変異体

Allele Name		tm1444
Balance		Not Required
OutCross		Not Accepted
Sequence Name		Y46G5A.26
Gene Name		lgc-35
Worm Base	Allele Name	tm1444
	Gene Name	lgc-35
	Sequence	Y46G5A.26
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr. E. Jorgensen: defecation cycle normal, slightly Dpy.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		158287/158288-159652/159653 (1365 bp deletion)
Chromosome		II
Putative gene structure		complement(join(157350..157447, 157480..157579, 157661..157800, 158190..158327, 158380..158498, 158737..159081, 159151..159281, 159346..159423))
Map position		11.62
Balancer
Map position of balancer
Sequence of primers		IntRev:CTAGCTTGCCGTCTGCAATA,ExtRev:CGCCTGACAGAAATTCATAC,IntFwd:CTGCGTCTCTTCTCCCCTAT,ExtFwd:CCACGTGATGTCAGCCTGAC
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Wang Z, Zhang Q, Jiang Y, Zhou J, Tian Y. ASI-RIM neuronal axis regulates systemic mitochondrial stress response via TGF-β signaling cascade. Nat Commun 2024 15(1) 8997  [ PubMed ID = 39426950 ] [ RRC reference ] Yuan F, Zhou J, Xu L, Jia W, Chun L, Xu XZS, Liu J. GABA receptors differentially regulate life span and health span in C. elegans through distinct downstream mechanisms. Am J Physiol Cell Physiol 2019 317(5) C953-C963  [ PubMed ID = 31433690 ] [ RRC reference ] Prior H, Jawad AK, MacConnachie L, Beg AA. Highly Efficient, Rapid and Co-CRISPR-Independent Genome Editing in Caenorhabditis elegans. G3 (Bethesda) 2017 7(11) 3693-3698  [ PubMed ID = 28893845 ] [ RRC reference ] Jobson MA, Valdez CM, Gardner J, Garcia LR, Jorgensen EM, Beg AA. Spillover transmission is mediated by the excitatory GABA receptor LGC-35 in C. elegans. J Neurosci 2015 35(6) 2803-16  [ PubMed ID = 25673867 ] [ RRC reference ]