Home > 分離済み変異体 > tm1443

分離済み変異体

Allele Name		tm1443
Balance		Completed
OutCross		Not Accepted
Sequence Name		T23G7.4
Gene Name		sec-5
Worm Base	Allele Name	tm1443 (x1)
	Gene Name	sec-5
	Sequence	T23G7.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		lethal or sterile. Dr. O. Blacque: could not examine Dyf phenotype. Dr. J. Lee: L1 arrest and Emb.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		12069/12070-12454/12455 (385 bp deletion)
Chromosome		II
Putative gene structure		complement(join(8510..8624, 8673..8967, 9638..9761, 9807..10145, 10194..10291, 10355..10649, 10696..11111, 11170..11404, 11457..11652, 11697..12065, 12114..12219, 12269..12335))
Map position		1.09
Balancer		mIn1,mIn1 [e128 mIs14]
Map position of balancer
Sequence of primers		ExtFwd:CATCTACCCAGACTGCGGAT,IntFwd:CTATTCGTACTTCACCGGGA,ExtRev:CACTCCAACCGTCTCTCCAC,IntRev:ATCGGCTGAGTTTCCGCTGC
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Liu S, Wei J, Zhong L, Hai S, Song S, Xie C, Huang Z, Cheng Z, Zhang J, Du A, Zhang P, Yan Y, Shi A. RAB-10 cooperates with EHBP-1 to capture vesicular carriers during post-Golgi exocytic trafficking. J Cell Biol 2025 224(4)   [ PubMed ID = 39982707 ] [ RRC reference ] Abrams J, Nance J. A polarity pathway for exocyst-dependent intracellular tube extension. Elife 2021 10   [ PubMed ID = 33687331 ] [ RRC reference ] Zou W, Yadav S, DeVault L, Nung Jan Y, Sherwood DR. RAB-10-Dependent Membrane Transport Is Required for Dendrite Arborization. PLoS Genet 2015 11(9) e1005484  [ PubMed ID = 26394140 ] [ RRC reference ] Chen S, Li L, Li J, Liu B, Zhu X, Zheng L, Zhang R, Xu T. SEC-10 and RAB-10 coordinate basolateral recycling of clathrin-independent cargo through endosomal tubules in Caenorhabditis elegans. Proc Natl Acad Sci U S A 2014 111(43) 15432-7  [ PubMed ID = 25301900 ] [ RRC reference ] Frische EW, Pellis-van Berkel W, van Haaften G, Cuppen E, Plasterk RH, Tijsterman M, Bos JL, Zwartkruis FJ. RAP-1 and the RAL-1/exocyst pathway coordinate hypodermal cell organization in Caenorhabditis elegans. EMBO J 2007 26(24) 5083-92  [ PubMed ID = 17989692 ] [ RRC reference ]