分離済み変異体

tm1420

Allele Nametm1420
BalanceNot Required
OutCrossNot Accepted
Sequence NameC34B2.7
Gene Namesdha-2
Worm BaseAllele Name tm1420
Gene Name sdha-2
Sequence C34B2.7
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. G. Ruvkun: no obvious phenotype.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 13799/13800-14318/14319 (519 bp deletion)
ChromosomeI
Putative gene structurecomplement(join(12661..13059, 13111..13300, 13344..13611, 13656..14330, 14376..14528, 14576..14754, 14808..14866))
Map position5.06
Balancer
Map position of balancer
Sequence of primersExtFwd:TTCACCAGCGGCATAGAGTC,IntFwd:TCGTAGGAACTCCTCCCATG,ExtRev:GCCAACACTCTGAGTACGCT,IntRev:TCTGAGTACGCTGGACCGAA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Cooper JF, Nguyen K, Gates D, Wolfrum E, Capan C, Lee H, Williams D, Okoye C, Wojtovich AP, Burton NO.
Oocyte mitochondria link maternal environment to offspring phenotype.
Res Sq 2024   
[ PubMed ID = 38585755 ] [ RRC reference ]

Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]

Horowitz BB, Nanda S, Walhout AJM.
A transcriptional cofactor regulatory network for the C. elegans intestine.
G3 (Bethesda) 2023 13(7)  
[ PubMed ID = 37119809 ] [ RRC reference ]

Woodhouse RM, Frolows N, Wang G, Hawdon A, Wong EHK, Dansereau LC, Su Y, Adair LD, New EJ, Philp AM, Tan WK, Philp A, Ashe A.
Mitochondrial succinate dehydrogenase function is essential for sperm motility and male fertility.
iScience 2022 25(12) 105573 
[ PubMed ID = 36465130 ] [ RRC reference ]

Bhattacharya S, Horowitz BB, Zhang J, Li X, Zhang H, Giese GE, Holdorf AD, Walhout AJM.
A metabolic regulatory network for the Caenorhabditis elegans intestine.
iScience 2022 25(8) 104688 
[ PubMed ID = 35847555 ] [ RRC reference ]

Otero L, Martínez-Rosales C, Barrera E, Pantano S, Salinas G.
Complex I and II Subunit Gene Duplications Provide Increased Fitness to Worms.
Front Genet 2019 10 1043 
[ PubMed ID = 31781156 ] [ RRC reference ]