分離済み変異体

tm1417

Allele Nametm1417
BalanceNot Required
OutCrossNot Accepted
Sequence NameZK1290.12
Gene Namewrt-1
Worm BaseAllele Name tm1417
Gene Name wrt-1
Sequence ZK1290.12
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 8567/8568-GAG-9218/9219 (651 bp deletion + 3 bp insertion)
ChromosomeII
Putative gene structurejoin(7876..8073, 8417..8589, 8634..8804, 8851..9482, 9553..9833)
Map position0.5
Balancer
Map position of balancer
Sequence of primersExtRev:TCTGTAACGCAGTTAGCCTT,IntFwd:TGTCTCTTCCTGACGGCTAC,ExtFwd:GTACAGACTGTCGCAGATTG,IntRev:CTGCGGAGTCATATCGATAA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Falsztyn IB, Jordan JM, Chen J, Zhao W, Chitrakar R, Reinke AW, Baugh LR.
Early life starvation and Hedgehog-related signaling activate innate immunity downstream of daf-18/PTEN and lin-35/Rb causing developmental pathology in adult C. elegans.
PLoS Genet 2025 21(12) e1011641 
[ PubMed ID = 41336845 ] [ RRC reference ]

Hall AN, Morton EA, Walters R, Cuperus JT, Queitsch C.
Phenotypic tolerance for rDNA copy number variation within the natural range of C. elegans.
PLoS Genet 2025 21(7) e1011759 
[ PubMed ID = 40601579 ] [ RRC reference ]

Baker EA, Gilbert SPR, Shimeld SM, Woollard A.
Extensive non-redundancy in a recently duplicated developmental gene family.
BMC Ecol Evol 2021 21(1) 33 
[ PubMed ID = 33648446 ] [ RRC reference ]

Roberts AF, Gumienny TL, Gleason RJ, Wang H, Padgett RW.
Regulation of genes affecting body size and innate immunity by the DBL-1/BMP-like pathway in Caenorhabditis elegans.
BMC Dev Biol 2010 10 61 
[ PubMed ID = 20529267 ] [ RRC reference ]