分離済み変異体

tm1397

Allele Nametm1397
BalanceCompleted
OutCrossNot Accepted
Sequence NameT05E11.5
Gene Nameimp-2
Worm BaseAllele Name tm1397 (x1)
Gene Name imp-2
Sequence T05E11.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile. Dr. H.C. Korswagen: Let.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 15246/15247-CAAACAAAAACAATGTTTCCA-15784/15785 (536 bp deletion + 21 bp insertion)
ChromosomeIV
Putative gene structurecomplement(join(13704..14231, 14512..15321, 15443..15511))
Map position4.89
BalancernT1 [qIs51]
Map position of balancer
Sequence of primersExtFwd:AGTCCAGCCATGTAAGCGAC,IntFwd:CCTTCGACTCGGCAGTCGTT,ExtRev:CCCTTCTCGACGTGTCCCTA,IntRev:GTCCCGCCCCAATTTGCAAG
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Grigorenko AP, Moliaka YK, Plotnikova OV, Smirnov A, Nikishina VA, Goltsov AY, Gusev F, Andreeva TV, Nelson O, Bezprozvanny I, Rogaev EI.
Mutational re-modeling of di-aspartyl intramembrane proteases: uncoupling physiologically-relevant activities from those associated with Alzheimer's disease.
Oncotarget 2017 8(47) 82006-82026 
[ PubMed ID = 29137240 ] [ RRC reference ]