分離済み変異体

tm1381

Allele Nametm1381
BalanceNot Required
OutCrossNot Accepted
Sequence NameC29E6.5
Gene Namenhr-43
Worm BaseAllele Name tm1381
Gene Name nhr-43
Sequence C29E6.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. C. Kenyon: normal lifespan.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 36465/36466-TTTGC-37007/37008 (542 bp deletion + 5 bp insertion)
ChromosomeIV
Putative gene structurejoin(36313..36371, 36907..37036, 37485..37578, 37647..37718, 38100..38349, 38401..38805, 38854..39121, 39172..39243)
Map position5.38
Balancer
Map position of balancer
Sequence of primersExtFwd:CCGCCTGTTTCCTGTGTAAT,IntFwd:GCGGCCCATTTCTTCACTTT,IntRev:TCGACGTCTAGGCGGGATTT,ExtRev:CATGTGCTTGAGAGAAAGCT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Zhi L, Yu Y, Li X, Wang D, Wang D.
Molecular Control of Innate Immune Response to Pseudomonas aeruginosa Infection by Intestinal let-7 in Caenorhabditis elegans.
PLoS Pathog 2017 13(1) e1006152 
[ PubMed ID = 28095464 ] [ RRC reference ]

Liu WJ, Reece-Hoyes JS, Walhout AJ, Eisenmann DM.
Multiple transcription factors directly regulate Hox gene lin-39 expression in ventral hypodermal cells of the C. elegans embryo and larva, including the hypodermal fate regulators LIN-26 and ELT-6.
BMC Dev Biol 2014 14 17 
[ PubMed ID = 24885717 ] [ RRC reference ]