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分離済み変異体

Allele Name		tm1375
Balance		Not Required
OutCross		Not Accepted
Sequence Name		C33G8.6
Gene Name		nhr-42
Worm Base	Allele Name	tm1375
	Gene Name	nhr-42
	Sequence	C33G8.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		19606/19607-AAT-20072/20073 (466 bp deletion + 3 bp insertion)
Chromosome		V
Putative gene structure		join(18885..18967, 19407..19725, 19771..19896, 19988..20051, 20100..20211, 20260..20375, 20422..20717)
Map position		0.5
Balancer
Map position of balancer
Sequence of primers		ExtFwd:CTGTCTTTTGCACTCTGCGT,IntFwd:GCGTCTCTCTTTGCCAATCT,IntRev:GCTGGCAGCAATGAAAACCA,ExtRev:GATGTTTTCCGTGCAGACCT
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Goswamy D, Gonzalez X, Labed SA, Irazoqui JE. C. elegans orphan nuclear receptor NHR-42 represses innate immunity and promotes lipid loss downstream of HLH-30/TFEB. Front Immunol 2023 14 1094145  [ PubMed ID = 36860863 ] [ RRC reference ] Lin CJ, Wang MC. Microbial metabolites regulate host lipid metabolism through NR5A-Hedgehog signalling. Nat Cell Biol 2017 19(5) 550-557  [ PubMed ID = 28436966 ] [ RRC reference ] Fuxman Bass JI, Pons C, Kozlowski L, Reece-Hoyes JS, Shrestha S, Holdorf AD, Mori A, Myers CL, Walhout AJ. A gene-centered C. elegans protein-DNA interaction network provides a framework for functional predictions. Mol Syst Biol 2016 12(10) 884  [ PubMed ID = 27777270 ] [ RRC reference ]