分離済み変異体

tm1322

Allele Nametm1322
BalanceCompleted
OutCrossNot Accepted
Sequence NameK02B12.4
Gene Nameaxl-1
Worm BaseAllele Name tm1322 (x1)
Gene Name axl-1
Sequence K02B12.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile. Dr. H.C. Korswagen: enhances the pry-1 (mu38) phenotype, axon guidance and excretory cell developmental defect.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 22145/22146-GTACTTTAACTTGTGGTTGACTCTCTGGTTG-22924/22925 (779 bp deletion + 31 bp insertion)
ChromosomeI
Putative gene structurejoin(22267..22332, 22971..23020, 23130..23255, 23299..23463, 23734..23810, 23859..23943, 23991..24150)
Map position2.89
BalancerhT2 [bli-4(e937) let-? qIs48]
Map position of balancer
Sequence of primersIntRev:CCCGTTGTTTGTTCCCGTAA,ExtFwd:CTACCCCACTTGCCATACTT,IntFwd:CGTTTTTCCGTAGAACCGCA,ExtRev:ATCTTTGCCACCATCGGAAC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Oosterveen T, Coudreuse DY, Yang PT, Fraser E, Bergsma J, Dale TC, Korswagen HC.
Two functionally distinct Axin-like proteins regulate canonical Wnt signaling in C. elegans.
Dev Biol 2007 308(2) 438-48 
[ PubMed ID = 17601533 ] [ RRC reference ]