Home > 分離済み変異体 > tm1307

分離済み変異体

Allele Name		tm1307
Balance		Not Required
OutCross		Not Accepted
Sequence Name		F16H11.5
Gene Name		nhr-45
Worm Base	Allele Name	tm1307
	Gene Name	nhr-45
	Sequence	F16H11.5
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr. J-C. Martinou: not hypersensitive nor hyperresistant to anoxia.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		12292/12293-GTCCCGTCATCCCGCCGGCGTGCGAGCGTGCGCCGCACAGTGGTTATTGTAAGACGATGGATTAGTGGACACACGTCCTTAAAACTGATTCAACAACGACAACGCTTCATTATCCTGTTTTGGTTTGTTCATTTTTAAAAGGGTTTTTCTAAGATATCACCTGATAGTAGGATTACTACGTTTTATTTCAAAGAAAACTCGGTGGATATATTTTTGAAGATGGTGCCGGTTTCTG-13837/13838 (1545 bp deletion + 235 bp insertion)
Chromosome		X
Putative gene structure		complement(join(10523..10624, 10701..10861, 10907..11025, 11086..11396, 11509..11613, 12150..12431, 13147..13430, 13566..13631, 13796..14006))
Map position		-6.92
Balancer
Map position of balancer
Sequence of primers		IntFwd:GGTTGCTTGTTGTGCGGCCA,ExtFwd:TGCATCAATAGTCGGCGTTA,IntRev:CCACATCACTTCACCTGGCT,ExtRev:ATGGCCGTCACCTCCATTGT
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Bhattacharya S, Horowitz BB, Zhang J, Li X, Zhang H, Giese GE, Holdorf AD, Walhout AJM. A metabolic regulatory network for the Caenorhabditis elegans intestine. iScience 2022 25(8) 104688  [ PubMed ID = 35847555 ] [ RRC reference ] Wallace SW, Lizzappi MC, Magemizoğlu E, Hur H, Liang Y, Shaham S. Nuclear hormone receptors promote gut and glia detoxifying enzyme induction and protect C. elegans from the mold P. brevicompactum. Cell Rep 2021 37(13) 110166  [ PubMed ID = 34965433 ] [ RRC reference ] Rossillo M, Ringstad N. Development of specialized sensory neurons engages a nuclear receptor required for functional plasticity. Genes Dev 2020 34(23-24) 1666-1679  [ PubMed ID = 33184226 ] [ RRC reference ] Arda HE, Taubert S, MacNeil LT, Conine CC, Tsuda B, Van Gilst M, Sequerra R, Doucette-Stamm L, Yamamoto KR, Walhout AJ. Functional modularity of nuclear hormone receptors in a Caenorhabditis elegans metabolic gene regulatory network. Mol Syst Biol 2010 6 367  [ PubMed ID = 20461074 ] [ RRC reference ]