分離済み変異体

tm1296

Allele Nametm1296
BalanceCompleted
OutCrossNot Accepted
Sequence NameY59A8B.23
Gene NameY59A8B.23
Worm BaseAllele Name tm1296 (x1)
Gene Name Y59A8B.23
Sequence Y59A8B.23
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 26157/26158-26790/26791 (633 bp deletion)
ChromosomeV
Putative gene structurecomplement(join(24567..24620, 25332..25492, 26591..27062, 28715..28993, 32724..32948, 33956..34183, 35580..35798))
Map position13.26
Balancerdpy-21 (e428) V
Map position of balancer
Sequence of primersIntFwd:AACGTTATCGACCGTCTATC,ExtRev:CGTCCAACAGCCTCCGAACT,IntRev:TCTCGCTTCAGTTCCAGTAG,ExtFwd:CCTCATTAGCGTGTACTCCA
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Murari E, Meadows D, Cuda N, Mangone M.
A comprehensive analysis of 3'UTRs in Caenorhabditis elegans.
Nucleic Acids Res 2024 52(13) 7523-7538 
[ PubMed ID = 38917330 ] [ RRC reference ]

Chen X, Wang K, Mufti FUD, Xu D, Zhu C, Huang X, Zeng C, Jin Q, Huang X, Yan YH, Dong MQ, Feng X, Shi Y, Kennedy S, Guang S.
Germ granule compartments coordinate specialized small RNA production.
Nat Commun 2024 15(1) 5799 
[ PubMed ID = 38987544 ] [ RRC reference ]

Weng Y, Murphy CT.
Male-specific behavioral and transcriptomic changes in aging C. elegans neurons.
iScience 2024 27(6) 109910 
[ PubMed ID = 38783998 ] [ RRC reference ]

Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]

Kupinski AP, Müller-Reichert T, Eckmann CR.
The Caenorhabditis elegans Ste20 kinase, GCK-3, is essential for postembryonic developmental timing and regulates meiotic chromosome segregation.
Dev Biol 2010 344(2) 758-71 
[ PubMed ID = 20595048 ] [ RRC reference ]

Hisamoto N, Moriguchi T, Urushiyama S, Mitani S, Shibuya H, Matsumoto K.
Caenorhabditis elegans WNK-STE20 pathway regulates tube formation by modulating ClC channel activity.
EMBO Rep 2008 9(1) 70-5 
[ PubMed ID = 18049475 ] [ RRC reference ]