Home > 分離済み変異体 > tm1287

分離済み変異体

Allele Name		tm1287
Balance		Not Required
OutCross		Not Accepted
Sequence Name		Y48A5A.2
Gene Name		ulp-3
Worm Base	Allele Name	tm1287
	Gene Name	ulp-3
	Sequence	Y48A5A.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr. H. Inoue: Healthy, fertile, normal growth rate, normal locomotion, normal response to touch and tap stimuli.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		3595/3596-3955/3956 (360 bp deletion)
Chromosome		IV
Putative gene structure		join(3216..3476, 3890..4261)
Map position		-12.64
Balancer
Map position of balancer
Sequence of primers		IntRev:CAGGTACTGTGCCACGTGGA,ExtRev:GCGTCCGCCGATTTTTGCTC,IntFwd:TCGGCCACCGATGAGCCATT,ExtFwd:CTACCCACTGGTACCGTATT
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Kassouf T, Shrivastava R, Meszka I, Bailly A, Polanowska J, Trauchessec H, Mandrioli J, Carra S, Xirodimas DP. Targeting the NEDP1 enzyme to ameliorate ALS phenotypes through stress granule disassembly. Sci Adv 2023 9(13) eabq7585  [ PubMed ID = 37000881 ] [ RRC reference ] Eck RJ, Stair JG, Kraemer BC, Liachko NF. Simple models to understand complex disease: 10 years of progress from Caenorhabditis elegans models of amyotrophic lateral sclerosis and frontotemporal lobar degeneration. Front Neurosci 2023 17 1300705  [ PubMed ID = 38239833 ] [ RRC reference ] Kreyden VA, Mawi EB, Rush KM, Kowalski JR. UBC-9 Acts in GABA Neurons to Control Neuromuscular Signaling in C. elegans. Neurosci Insights 2020 15 2633105520962792  [ PubMed ID = 33089216 ] [ RRC reference ] Bailly AP, Perrin A, Serrano-Macia M, Maghames C, Leidecker O, Trauchessec H, Martinez-Chantar ML, Gartner A, Xirodimas DP. The Balance between Mono- and NEDD8-Chains Controlled by NEDP1 upon DNA Damage Is a Regulatory Module of the HSP70 ATPase Activity. Cell Rep 2019 29(1) 212-224.e8  [ PubMed ID = 31577950 ] [ RRC reference ]