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分離済み変異体

Allele Name		tm1275
Balance		Not Required
OutCross		Not Accepted
Sequence Name		W09D10.2
Gene Name		tat-3
Worm Base	Allele Name	tm1275
	Gene Name	tat-3
	Sequence	W09D10.2
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr. S. Tuck: no obvious defects in endocytosis. Dr. M. Han: normal growth rate.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		21820/21822-ANACAGA-22267/22268 (446 bp deletion + 7 bp insertion)
Chromosome		III
Putative gene structure		complement(join(15836..15856, 16246..16334, 16406..16541, 17071..17337, 17514..17966, 18591..19433, 19944..20213, 20484..21140, 21294..21491, 21546..22016, 22109..22711))
Map position		5.05
Balancer
Map position of balancer
Sequence of primers		ExtFwd:CGGACGACCTCCATAGTCAT,IntFwd:ACTGAGCATCGGCGGAATAC,ExtRev:CTCATTATGGGTACCCCCGA,IntRev:GTACCCCCGACACGGTAATT
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Nilsson L, Jonsson E, Tuck S. Caenorhabditis elegans numb inhibits endocytic recycling by binding TAT-1 aminophospholipid translocase. Traffic 2011 12(12) 1839-49  [ PubMed ID = 21917090 ] [ RRC reference ] Seamen E, Blanchette JM, Han M. P-type ATPase TAT-2 negatively regulates monomethyl branched-chain fatty acid mediated function in post-embryonic growth and development in C. elegans. PLoS Genet 2009 5(8) e1000589  [ PubMed ID = 19662161 ] [ RRC reference ] Lyssenko NN, Miteva Y, Gilroy S, Hanna-Rose W, Schlegel RA. An unexpectedly high degree of specialization and a widespread involvement in sterol metabolism among the C. elegans putative aminophospholipid translocases. BMC Dev Biol 2008 8 96  [ PubMed ID = 18831765 ] [ RRC reference ] Darland-Ransom M, Wang X, Sun CL, Mapes J, Gengyo-Ando K, Mitani S, Xue D. Role of C. elegans TAT-1 protein in maintaining plasma membrane phosphatidylserine asymmetry. Science 2008 320(5875) 528-31  [ PubMed ID = 18436785 ] [ RRC reference ]