Home > 分離済み変異体 > tm1268

分離済み変異体

Allele Name		tm1268
Balance		Completed
OutCross		Not Accepted
Sequence Name		W06D4.6
Gene Name		rad-54
Worm Base	Allele Name	tm1268 (x1)
	Gene Name	rad-54
	Sequence	W06D4.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		lethal or sterile. Dr. S. Boulton: sterile, abnormal meiosis. Dr. M. Hengartner: maternal effect Emb, increased level of apoptosis. Dr. M. Jantsch: no meiotic phenotype.
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		16239/16240-17050/17051 (811 bp deletion)
Chromosome		I
Putative gene structure		join(15017..15120, 15535..15613, 15687..15930, 15974..16113, 16213..16558, 16632..16756, 16802..16920, 16965..17042, 17090..17216, 17265..17372, 17418..17526, AL110471.1:303..469, AL110471.1:860..1201, AL110471.1:1629..1726, AL110471.1:1848..1959, AL110471.1:2003..2077, AL110471.1:2369..2452)
Map position		3.49
Balancer		hT2
Map position of balancer
Sequence of primers		ExtRev:CAGATGCGGTGGCACCCTAA,IntRev:GGCGTCGCGACCTCTAGAAA,ExtFwd:GAAGGCACTGCCTGCCATAG,IntFwd:GCCTGCCATAGAACCACCTG
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Lawrence KS, Tapley EC, Cruz VE, Li Q, Aung K, Hart KC, Schwartz TU, Starr DA, Engebrecht J. LINC complexes promote homologous recombination in part through inhibition of nonhomologous end joining. J Cell Biol 2016 215(6) 801-821  [ PubMed ID = 27956467 ] [ RRC reference ] Stamper EL, Rodenbusch SE, Rosu S, Ahringer J, Villeneuve AM, Dernburg AF. Identification of DSB-1, a protein required for initiation of meiotic recombination in Caenorhabditis elegans, illuminates a crossover assurance checkpoint. PLoS Genet 2013 9(8) e1003679  [ PubMed ID = 23990794 ] [ RRC reference ] Stergiou L, Eberhard R, Doukoumetzidis K, Hengartner MO. NER and HR pathways act sequentially to promote UV-C-induced germ cell apoptosis in Caenorhabditis elegans. Cell Death Differ 2011 18(5) 897-906  [ PubMed ID = 21151025 ] [ RRC reference ] Ward JD, Muzzini DM, Petalcorin MI, Martinez-Perez E, Martin JS, Plevani P, Cassata G, Marini F, Boulton SJ. Overlapping mechanisms promote postsynaptic RAD-51 filament disassembly during meiotic double-strand break repair. Mol Cell 2010 37(2) 259-72  [ PubMed ID = 20122407 ] [ RRC reference ]