分離済み変異体

tm1262

Allele Nametm1262
Allele Type通常株
Sequence NameW01A11.4
Gene Namelec-10
Worm BaseAllele Name tm1262
Gene Name lec-10
Sequence W01A11.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. K. Kasai: Biol. Pharmac. bulletin, 32, 1973 (2009).
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 23664/23665-24436/24437 (772 bp deletion)
ChromosomeV
Putative gene structurecomplement(join(23332..23607, 23656..23937, 24005..24025))
Map position-0.1
Balancer
Map position of balancer
Sequence of primersIntFwd:CCAGAGTGTCCATGATCGAC,ExtFwd:TGCCTAATAGGCGGCCTTCA,IntRev:GTGACTTGAATTCGCACCCT,ExtRev:TAGCATCACGTTGTGTGTGC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Maduzia LL, Yu E, Zhang Y.
Caenorhabditis elegans galectins LEC-6 and LEC-10 interact with similar glycoconjugates in the intestine.
J Biol Chem 2011 286(6) 4371-81 
[ PubMed ID = 21115491 ] [ RRC reference ]

Takeuchi T, Nemoto-Sasaki Y, Sugiura K, Arata Y, Kasai K.
Galectin LEC-1 plays a defensive role against damage due to oxidative stress in Caenorhabditis elegans.
J Biochem 2013 154(5) 455-64 
[ PubMed ID = 23935187 ] [ RRC reference ]

Nemoto-Sasaki Y, Kasai K.
Deletion of lec-10, a galectin-encoding gene, increases susceptibility to oxidative stress in Caenorhabditis elegans.
Biol Pharm Bull 2009 32(12) 1973-7 
[ PubMed ID = 19952414 ] [ RRC reference ]