分離済み変異体

tm12491

Allele Nametm12491
BalanceNot Required
OutCrossRequest Available
Sequence NameK12H4.8
Gene Namedcr-1
Worm BaseAllele Name tm12491
Gene Name dcr-1
Sequence K12H4.8
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 30597/30598-30720/30721(123 bp deletion)
ChromosomeIII
Putative gene structurecomplement(join(29981..30181, 30234..30613, 30716..30811, 30860..31106, 31165..31331, 31381..31527, 31578..31764, 31821..32046, 32615..32930, 32974..33279, 33329..33510, 33557..34149, 34210..34540, 34658..34808, 34859..34927, 34969..35148, 35257..35623, 35692..35846, 35893..36135, 36180..36308, 36353..36535, 36968..37339, 37392..37531, 37597..37756, 37802..37935, 38030..38192, 38238..38295))
Map position-0.39
Balancer
Map position of balancer
Sequence of primersExtRev:CATTGACACTCCGACCAATC,ExtFwd:TCGAACTCCATAAGCTCTCG
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Mazzetto M, Gonzalez LE, Sanchez N, Reinke V.
Characterization of the distribution and dynamics of chromatin states in the C. elegans germline reveals substantial H3K4me3 remodeling during oogenesis.
Genome Res 2024 34(1) 57-69 
[ PubMed ID = 38164610 ] [ RRC reference ]

Braun M, Shoshani S, Teixeira J, Mellul Shtern A, Miller M, Granot Z, Fischer SEJ, Garcia SMDA, Tabach Y.
Asymmetric inheritance of RNA toxicity in C. elegans expressing CTG repeats.
iScience 2022 25(5) 104246 
[ PubMed ID = 35494247 ] [ RRC reference ]

Okabe E, Uno M, Kishimoto S, Nishida E.
Intertissue small RNA communication mediates the acquisition and inheritance of hormesis in Caenorhabditis elegans.
Commun Biol 2021 4(1) 207 
[ PubMed ID = 33594200 ] [ RRC reference ]