分離済み変異体

tm1234

Allele Nametm1234
BalanceCompleted
OutCrossNot Accepted
Sequence NameF58G11.1a
Gene Nameletm-1
Worm BaseAllele Name tm1234 (x1)
Gene Name letm-1
Sequence F58G11.1a
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" lethal or sterile. Dr. A. van der Bliek: Human Mol. Genetics 16, 2061 (2007).
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 1561/1562-TTTTCAGGAAGAAAA-2098/2099 (537 bp deletion + 15 bp insertion)
ChromosomeV
Putative gene structurejoin(1449..1579, 1639..2059, 2108..2634, 2686..3730, 3780..3926, 4030..4113)
Map position5.57
BalancernT1,nT1 [qIs51]
Map position of balancer
Sequence of primersExtFwd:CTGGCTTATGGGATCGTCAT,IntFwd:GTTTTAACTCCCGATTGCGA,ExtRev:CGCTGTTCTCCACGGTTGGA,IntRev:AGCGAATGCACCATCTAGAG
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Hasegawa A, van der Bliek AM.
Inverse correlation between expression of the Wolfs Hirschhorn candidate gene Letm1 and mitochondrial volume in C. elegans and in mammalian cells.
Hum Mol Genet 2007 16(17) 2061-71 
[ PubMed ID = 17606466 ] [ RRC reference ]