分離済み変異体

tm12210

Allele Nametm12210
BalanceNot Required
OutCrossCompleted
Sequence NameC25B8.3
Gene Namecpr-6
Worm BaseAllele Name tm12210 (x1)
Gene Name cpr-6
Sequence C25B8.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 3924/3925-4081/4082(157 bp deletion)
ChromosomeX
Putative gene structurejoin(2287..2289, 2339..2414, 2462..2556, 2600..2695, 2889..3230, 3285..3557, 3605..3822, 3969..4005)
Map position-2.74
Balancer
Map position of balancer
Sequence of primersExtFwd:CACGATTTGTACCCAACTCC,ExtRev:GAGAACAACAGCACGAAAAC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Siddiqui AA, Merquiol E, Bruck-Haimson R, Hirbawi J, Boocholez H, Cohen I, Yan Y, Dong MQ, Blum G, Cohen E.
Cathepsin B promotes Aβ proteotoxicity by modulating aging regulating mechanisms.
Nat Commun 2024 15(1) 8564 
[ PubMed ID = 39362844 ] [ RRC reference ]