分離済み変異体

tm1220

Allele Nametm1220
Allele Type通常株
Sequence NameZK652.11
Gene Namecuc-1
Worm BaseAllele Name tm1220
Gene Name cuc-1
Sequence ZK652.11
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 33170/33171-33494/33495 (324 bp deletion)
ChromosomeIII
Putative gene structurecomplement(join(32409..32536, 32583..32655, 32735..32743))
Map position-0.54
Balancer
Map position of balancer
Sequence of primersIntFwd:CCCTCTTTCCGCCATGAGTC,ExtRev:TGCAGACTGCGTATGCGACA,ExtFwd:GCAATCCAATGGGGATTCGT,IntRev:GCGACACCATACTTGACGAC
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Weishaupt AK, Gremme A, Meiners T, Schwantes V, Sarnow K, Thiel A, Schwerdtle T, Aschner M, Hayen H, Bornhorst J.
Dysfunctional copper homeostasis in Caenorhabditis elegans affects genomic and neuronal stability.
Redox Biochem Chem 2024 10  
[ PubMed ID = 39726988 ] [ RRC reference ]

Weishaupt AK, Lamann K, Tallarek E, Pezacki AT, Matier CD, Schwerdtle T, Aschner M, Chang CJ, Stürzenbaum SR, Bornhorst J.
Dysfunction in atox-1 and ceruloplasmin alters labile Cu levels and consequently Cu homeostasis in C. elegans.
Front Mol Biosci 2024 11 1354627 
[ PubMed ID = 38389896 ] [ RRC reference ]

Fields BD, Kennedy S.
Chromatin Compaction by Small RNAs and the Nuclear RNAi Machinery in C. elegans.
Sci Rep 2019 9(1) 9030 
[ PubMed ID = 31227740 ] [ RRC reference ]

Yeon J, Kim J, Kim DY, Kim H, Kim J, Du EJ, Kang K, Lim HH, Moon D, Kim K.
A sensory-motor neuron type mediates proprioceptive coordination of steering in C. elegans via two TRPC channels.
PLoS Biol 2018 16(6) e2004929 
[ PubMed ID = 29883446 ] [ RRC reference ]