分離済み変異体

tm1203

Allele Name

tm1203

Balance

Not Required

OutCross

Not Accepted

Sequence Name

R07E5.8

Gene Name

cku-80

Worm Base

Allele Name

tm1203

Gene Name

cku-80

Sequence

R07E5.8

Phenotype

homozygous viable.Dr. T. Schedl: could not recover mutants. Dr. S. Ahmed: Genetics 173, 1301-1317 (2006). Dr. J-L. Bessereau: in frame deletion and no phenotype.

Mutation site

27310/27311-27901/27902 (591 bp deletion)

Chromosome

III

Putative gene structure

join(26798..26938, 26986..27181, 27231..27408, 27455..27538, 27861..27933, 27984..28394, 28840..29155, 29208..29268, 29314..29399, 29453..29871, 29924..30056, 30110..30198)

Map position

-3.17

Balancer

Map position of balancer

Sequence of primers

ExtFwd:TGACGGTGAACTGTCCGCGT,IntFwd:ACTGTCCGCGTGCACCAGAT,ExtRev:ACATTCTCCGTCGTTGCGAG,IntRev:TAGCACTCCACCAGTCTGTC

Distributed lab

Depositor

Dr. S. Mitani/NBRP

References

Please submit your publication

Suehiro Y, Yoshina S, Motohashi T, Iwata S, Dejima K, Mitani S.
Efficient collection of a large number of mutations by mutagenesis of DNA damage response defective animals.
Sci Rep 2021 11(1) 7630
[ PubMed ID = 33828169 ] [ RRC reference ]

Vujin A, Jones SJ, Zetka M.
NHJ-1 Is Required for Canonical Nonhomologous End Joining in Caenorhabditis elegans.
Genetics 2020 215(3) 635-651
[ PubMed ID = 32457132 ] [ RRC reference ]

Li X, O'Neil NJ, Moshgabadi N, Hieter P.
Synthetic cytotoxicity: digenic interactions with TEL1/ATM mutations reveal sensitivity to low doses of camptothecin.
Genetics 2014 197(2) 611-23
[ PubMed ID = 24653001 ] [ RRC reference ]

Lowden MR, Meier B, Lee TW, Hall J, Ahmed S.
End joining at Caenorhabditis elegans telomeres.
Genetics 2008 180(2) 741-54
[ PubMed ID = 18780750 ] [ RRC reference ]

Clejan I, Boerckel J, Ahmed S.
Developmental modulation of nonhomologous end joining in Caenorhabditis elegans.
Genetics 2006 173(3) 1301-17
[ PubMed ID = 16702421 ] [ RRC reference ]