Home > 分離済み変異体 > tm1192

分離済み変異体

Allele Name		tm1192
Balance		Not Required
OutCross		Not Accepted
Sequence Name		F20B4.6
Gene Name		cgt-2
Worm Base	Allele Name	tm1192
	Gene Name	cgt-2
	Sequence	F20B4.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		9308/9309-AG-9661/9662 (353 bp deletion + 2 bp insertion)
Chromosome		X
Putative gene structure		join(6817..7064, 8321..8556, 8602..8822, 9048..9371, 10039..10170, 11596..11766)
Map position		24.62
Balancer
Map position of balancer
Sequence of primers		ExtFwd:CCACGCATCTTATGGCTGTA,IntFwd:TGCAGAAGGGAAGCAATCCT,ExtRev:GAAAGTATCGACTCCACCGT,IntRev:CCAACCCTTCACTACCCGGA
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Luo H, Zhao X, Wang ZD, Wu G, Xia Y, Dong MQ, Ma Y. Sphingolipid profiling reveals differential functions of sphingolipid biosynthesis isozymes of Caenorhabditis elegans. J Lipid Res 2024 65(6) 100553  [ PubMed ID = 38704027 ] [ RRC reference ] Arvin CL, Sibila Z, Lamendella R, Chan J, Staab T. The impact of C. elegans ceramide glucosyltransferase enzymes on the beneficial effects of B. subtilis lifespan. MicroPubl Biol 2023 2023   [ PubMed ID = 37090153 ] [ RRC reference ] Li N, Hua B, Chen Q, Teng F, Ruan M, Zhu M, Zhang L, Huo Y, Liu H, Zhuang M, Shen H, Zhu H. A sphingolipid-mTORC1 nutrient-sensing pathway regulates animal development by an intestinal peroxisome relocation-based gut-brain crosstalk. Cell Rep 2022 40(4) 111140  [ PubMed ID = 35905721 ] [ RRC reference ] Nomura KH, Murata D, Hayashi Y, Dejima K, Mizuguchi S, Kage-Nakadai E, Gengyo-Ando K, Mitani S, Hirabayashi Y, Ito M, Nomura K. Ceramide glucosyltransferase of the nematode Caenorhabditis elegans is involved in oocyte formation and in early embryonic cell division. Glycobiology 2011 21(6) 834-48  [ PubMed ID = 21325339 ] [ RRC reference ] Marza E, Simonsen KT, Faergeman NJ, Lesa GM. Expression of ceramide glucosyltransferases, which are essential for glycosphingolipid synthesis, is only required in a small subset of C. elegans cells. J Cell Sci 2009 122(Pt 6) 822-33  [ PubMed ID = 19240113 ] [ RRC reference ]