分離済み変異体

tm1156

Allele Nametm1156
BalanceNot Required
OutCrossNot Accepted
Sequence NameY66A7A.6
Gene Namegly-8
Worm BaseAllele Name tm1156
Gene Name gly-8
Sequence Y66A7A.6
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s) [Y66A7AR] 15318/15319-[Y66A7AR] 16256/16257 (938 bp deletion)
ChromosomeIII
Putative gene structurejoin(14766..14872, 15159..15237, 15293..15396, 15919..16171, 16249..16382, 16429..16587, 16635..16752, 17368..17520, 17566..17724)
Map position11.36
Balancer
Map position of balancer
Sequence of primersExtRev:CGATATGTCGGGCGCAACCT,IntRev:CAACCTCGCCTCCACATAGT,ExtFwd:TACAGAATGCGACGCCACGT,IntFwd:CGCCACGTCGTCCTATCGAT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Wang Z, Zhang Q, Jiang Y, Zhou J, Tian Y.
ASI-RIM neuronal axis regulates systemic mitochondrial stress response via TGF-β signaling cascade.
Nat Commun 2024 15(1) 8997 
[ PubMed ID = 39426950 ] [ RRC reference ]

Eck RJ, Stair JG, Kraemer BC, Liachko NF.
Simple models to understand complex disease: 10 years of progress from Caenorhabditis elegans models of amyotrophic lateral sclerosis and frontotemporal lobar degeneration.
Front Neurosci 2023 17 1300705 
[ PubMed ID = 38239833 ] [ RRC reference ]

Tsai HY, Cheng HT, Tsai YT.
Biogenesis of C. elegans spermatogenesis small RNAs is initiated by a zc3h12a-like ribonuclease.
Sci Adv 2022 8(32) eabm0699 
[ PubMed ID = 35947655 ] [ RRC reference ]

Liachko NF, Saxton AD, McMillan PJ, Strovas TJ, Keene CD, Bird TD, Kraemer BC.
Genome wide analysis reveals heparan sulfate epimerase modulates TDP-43 proteinopathy.
PLoS Genet 2019 15(12) e1008526 
[ PubMed ID = 31834878 ] [ RRC reference ]