分離済み変異体

tm1136

Allele Nametm1136
Allele Type通常株
Sequence NameC52A11.4
Gene Namempz-1
Worm BaseAllele Name tm1136
Gene Name mpz-1
Sequence C52A11.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable, Dr. C. Rongo: normal. GLR-1::GFP expression. Dr. K.Shen: Normal HSN vulval presynaptic vesicle clusters (unc-86::SNB-1::YFP), no obvious egg laying defects. Dr. M. Treinin: no defects in PVD morphology.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 38918/38919-TTG-40042/40043 (1124 bp deletion + 3 bp insertion)
ChromosomeII
Putative gene structurecomplement(join(15359..15442, 15744..15890, 15937..16077, 16214..16522, 17581..18179, 18572..18638, 22778..22979, 23139..24064, 24328..24561, 24612..25181, 25940..26014, 27138..27257, 27306..27432, 27547..27645, 27809..27915, 28210..28390, 28440..28516, 29617..29671, 30095..30169, 31201..31223, 32816..32900, 33134..33267, 33578..33863, 34037..34557, 34973..35064, 35443..35566, 35688..35833, 35877..36028, 36161..36339, 36497..36564, 39825..39978, 40215..40349, Z46795.1:763..863, Z46795.1:1346..1497, Z46795.1:2445..2524))
Map position2.85
Balancer
Map position of balancer
Sequence of primersExtFwd:CGTAGTGTTTTCAGTCGCTA,IntFwd:GTGTGTTGCGGTCAGACTAT,ExtRev:CAGTCCTGCAGATAAAGTGA,IntRev:TGGCCGGAATCTGCTAAACT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Dillon J, Holden-Dye L, O'Connor V.
Yeast two-hybrid screening identifies MPZ-1 and PTP-1 as candidate scaffolding proteins of metabotropic glutamate receptors in Caenorhabditis elegans.
Invert Neurosci 2018 18(4) 16 
[ PubMed ID = 30417267 ] [ RRC reference ]