分離済み変異体

tm1113

Allele Nametm1113
BalanceNot Required
OutCrossNot Accepted
Sequence NameZK1248.7
Gene Namewago-5
Worm BaseAllele Name tm1113
Gene Name wago-5
Sequence ZK1248.7
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. C. Mello, Cell 127, 747-457 (2006).
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 3509/3510-4099/4100 (590 bp deletion)
ChromosomeII
Putative gene structurecomplement(join(2854..2965, 3022..3317, 3360..3599, 3648..3994, 4045..4220, 4264..4419, 4458..5192, 5236..5816, 5866..5961))
Map position-0.93
Balancer
Map position of balancer
Sequence of primersExtRev:GATTCGAGTTGCCGATGGGA,IntRev:GACGTGTTCAATCGCCGAGT,ExtFwd:GGTGATAGAGCAAGCGAACT,IntFwd:AAGTATGAGGATGCACCGTT
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Palominos MF, Verdugo L, Gabaldon C, Pollak B, Ortíz-Severín J, Varas MA, Chávez FP, Calixto A.
Transgenerational Diapause as an Avoidance Strategy against Bacterial Pathogens in Caenorhabditis elegans.
mBio 2017 8(5)  
[ PubMed ID = 29018118 ] [ RRC reference ]

Zhou X, Xu F, Mao H, Ji J, Yin M, Feng X, Guang S.
Nuclear RNAi contributes to the silencing of off-target genes and repetitive sequences in Caenorhabditis elegans.
Genetics 2014 197(1) 121-32 
[ PubMed ID = 24532782 ] [ RRC reference ]

Hall SE, Chirn GW, Lau NC, Sengupta P.
RNAi pathways contribute to developmental history-dependent phenotypic plasticity in C. elegans.
RNA 2013 19(3) 306-19 
[ PubMed ID = 23329696 ] [ RRC reference ]

Gu W, Shirayama M, Conte D Jr, Vasale J, Batista PJ, Claycomb JM, Moresco JJ, Youngman EM, Keys J, Stoltz MJ, Chen CC, Chaves DA, Duan S, Kasschau KD, Fahlgren N, Yates JR 3rd, Mitani S, Carrington JC, Mello CC.
Distinct argonaute-mediated 22G-RNA pathways direct genome surveillance in the C. elegans germline.
Mol Cell 2009 36(2) 231-44 
[ PubMed ID = 19800275 ] [ RRC reference ]