分離済み変異体

tm1111

Allele Nametm1111
BalanceNot Required
OutCrossNot Accepted
Sequence NameF13B10.1a
Gene Nametir-1
Worm BaseAllele Name tm1111
Gene Name tir-1
Sequence F13B10.1a
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. C. Bargmann: Genes & Dev.19, 270-281, 2005. Dr. J. Ewbank: normal induction of nlp-29 after infection by D. coniospora. Dr. R. Shingai: normal chemotaxis to simultaneously presented Na-acetate and diacetyl.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 13185/13186-ATGAAANANAACAA-13973/13974 (788 bp deletion + 14 bp insertion)
ChromosomeIII
Putative gene structurecomplement(join(1550..1644, 1693..1810, 1967..3001, 11483..11597, 11646..12023, 12324..12442, 12490..12720, 12998..13372, 13674..13914, 22291..22376))
Map position-4.25
Balancer
Map position of balancer
Sequence of primersIntFwd:CGTGTCGAAGGATGTCGGGA,ExtFwd:TAGGATGTTGGCCAACGCAA,IntRev:GGAACAACGGCGCCACCTAA,ExtRev:TCCTGGAGATCGCCTCTGCA
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Shivers RP, Kooistra T, Chu SW, Pagano DJ, Kim DH.
Tissue-specific activities of an immune signaling module regulate physiological responses to pathogenic and nutritional bacteria in C. elegans.
Cell Host Microbe 2009 6(4) 321-30 
[ PubMed ID = 19837372 ] [ RRC reference ]

Pujol N, Cypowyj S, Ziegler K, Millet A, Astrain A, Goncharov A, Jin Y, Chisholm AD, Ewbank JJ.
Distinct innate immune responses to infection and wounding in the C. elegans epidermis.
Curr Biol 2008 18(7) 481-9 
[ PubMed ID = 18394898 ] [ RRC reference ]

Bauer Huang SL, Saheki Y, VanHoven MK, Torayama I, Ishihara T, Katsura I, van der Linden A, Sengupta P, Bargmann CI.
Left-right olfactory asymmetry results from antagonistic functions of voltage-activated calcium channels and the Raw repeat protein OLRN-1 in C. elegans.
Neural Dev 2007 2 24 
[ PubMed ID = 17986337 ] [ RRC reference ]

Ceron J, Rual JF, Chandra A, Dupuy D, Vidal M, van den Heuvel S.
Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity.
BMC Dev Biol 2007 7 30 
[ PubMed ID = 17417969 ] [ RRC reference ]

Chuang CF, Bargmann CI.
A Toll-interleukin 1 repeat protein at the synapse specifies asymmetric odorant receptor expression via ASK1 MAPKKK signaling.
Genes Dev 2005 19(2) 270-81 
[ PubMed ID = 15625192 ] [ RRC reference ]