分離済み変異体

tm1110

Allele Nametm1110
Allele Type通常株
Sequence NameF56F11.3
Gene Nameklf-1
Worm BaseAllele Name tm1110
Gene Name klf-1
Sequence F56F11.3
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. M. Bastiani: no axon regeneration phenotype.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 26930/26931-27421/27422 (491 bp deletion)
ChromosomeIII
Putative gene structurejoin(24132..24267, 24829..25001, 25915..26107, 26901..26981, 27567..27863, 28534..28971, 29334..29423, 29578..29663)
Map position-9.93
Balancer
Map position of balancer
Sequence of primersIntFwd:AATGACCGTCTGGAACAGAT,ExtFwd:ACTCAACTCAGAGCCTTTTC,ExtRev:TCGGACTATCCATGTCAGCA,IntRev:GCATCCTCCACAACAATACT
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Herholz M, Cepeda E, Baumann L, Kukat A, Hermeling J, Maciej S, Szczepanowska K, Pavlenko V, Frommolt P, Trifunovic A.
KLF-1 orchestrates a xenobiotic detoxification program essential for longevity of mitochondrial mutants.
Nat Commun 2019 10(1) 3323 
[ PubMed ID = 31346165 ] [ RRC reference ]

Nix P, Hammarlund M, Hauth L, Lachnit M, Jorgensen EM, Bastiani M.
Axon regeneration genes identified by RNAi screening in C. elegans.
J Neurosci 2014 34(2) 629-45 
[ PubMed ID = 24403161 ] [ RRC reference ]

Carrano AC, Dillin A, Hunter T.
A Krüppel-like factor downstream of the E3 ligase WWP-1 mediates dietary-restriction-induced longevity in Caenorhabditis elegans.
Nat Commun 2014 5 3772 
[ PubMed ID = 24805825 ] [ RRC reference ]