分離済み変異体

tm1092

Allele Nametm1092
BalanceNot Required
OutCrossNot Accepted
Sequence NameF07G6.1
Gene Namedgn-3
Worm BaseAllele Name tm1092
Gene Name dgn-3
Sequence F07G6.1
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. S. McIntire: normal development and locomotion.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 27727/27728-28456/28457 (729 bp deletion)
ChromosomeX
Putative gene structurejoin(27429..27742, 28949..29363, 29478..29629, 29675..29789)
Map position-17.65
Balancer
Map position of balancer
Sequence of primersExtFwd:GCGAGCTTATGAGAGCCCTA,IntFwd:CTCCGAGCTGACACTTGGAT,IntRev:TCTTCCAGCACTGCGTTTCT,ExtRev:TGTCGCCACTCTCCGATAGT
Distributed lab
DepositorDr. S. Mitani/NBRP
References Please submit your publication
Teuscher AC, Statzer C, Goyala A, Domenig SA, Schoen I, Hess M, Hofer AM, Fossati A, Vogel V, Goksel O, Aebersold R, Ewald CY.
Longevity interventions modulate mechanotransduction and extracellular matrix homeostasis in C. elegans.
Nat Commun 2024 15(1) 276 
[ PubMed ID = 38177158 ] [ RRC reference ]

Qin J, Liang J, Ding M.
Perlecan antagonizes collagen IV and ADAMTS9/GON-1 in restricting the growth of presynaptic boutons.
J Neurosci 2014 34(31) 10311-24 
[ PubMed ID = 25080592 ] [ RRC reference ]

Trzebiatowska A, Topf U, Sauder U, Drabikowski K, Chiquet-Ehrismann R.
Caenorhabditis elegans teneurin, ten-1, is required for gonadal and pharyngeal basement membrane integrity and acts redundantly with integrin ina-1 and dystroglycan dgn-1.
Mol Biol Cell 2008 19(9) 3898-908 
[ PubMed ID = 18632986 ] [ RRC reference ]