Home > 分離済み変異体 > tm1075

分離済み変異体

Allele Name		tm1075
Balance		Not Required
OutCross		Not Accepted
Sequence Name		F28H6.1a
Gene Name		akt-2
Worm Base	Allele Name	tm1075
	Gene Name	akt-2
	Sequence	F28H6.1a
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable. Dr. W.B. Derry: Current Biol. 17, 286 (2007).
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		36891/36892-37473/37474 (582 bp deletion)
Chromosome		X
Putative gene structure		join(35289..35383, 35587..35695, 36588..36788, 36832..36951, 37176..37373, 37845..37975, Z92837:104..164, Z92837:275..403, Z92837:451..813, Z92837:1091..1270)
Map position		16.55
Balancer
Map position of balancer
Sequence of primers		ExtFwd:TTATGCGGATAGCGCCGACT,IntFwd:GTCAGATGTGGATTGAAGCA,ExtRev:CTGTCGGAAGTTCTTCCCCT,IntRev:TCTACGTGGAGGCGTCAGTT
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Nakagawa A, Sullivan KD, Xue D. Caspase-activated phosphoinositide binding by CNT-1 promotes apoptosis by inhibiting the AKT pathway. Nat Struct Mol Biol 2014 21(12) 1082-90  [ PubMed ID = 25383666 ] [ RRC reference ] Nawa M, Kage-Nakadai E, Aiso S, Okamoto K, Mitani S, Matsuoka M. Reduced expression of BTBD10, an Akt activator, leads to motor neuron death. Cell Death Differ 2012 19(8) 1398-407  [ PubMed ID = 22388351 ] [ RRC reference ] Quevedo C, Kaplan DR, Derry WB. AKT-1 regulates DNA-damage-induced germline apoptosis in C. elegans. Curr Biol 2007 17(3) 286-92  [ PubMed ID = 17276923 ] [ RRC reference ]