分離済み変異体

tm1062

Allele Nametm1062
BalanceNot Required
OutCrossNot Accepted
Sequence NameK09G1.4
Gene Namedop-2
Worm BaseAllele Name tm1062
Gene Name dop-2
Sequence K09G1.4
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype" homozygous viable. Dr. S. McIntire: not lethal when outcrossed. Dr. C. Kenyon: does not affect daf-2 dauer at 25 C.
Mutation site Please see gene structure to locate the deletion in relation to exon(s) 28188/28189-TTTATGGTTTTTCATTTTT-28617/28618 (429 bp deletion + 19 bp insertion)
ChromosomeV
Putative gene structurejoin(27218..27784, 28264..28386, 29529..29641, 29855..29976, 30031..30138, 30189..30285, 30331..30398, 31766..31880, 32327..32515, 32562..32830, 32876..33390, 33467..33610, 33661..33831)
Map position2.06
Balancer
Map position of balancer
Sequence of primersExtRev:GTGGTTGGAAGGATCTAGGA,IntRev:CGGCTTTCCGTGCATCTAAT,ExtFwd:ACAGTCATCTGAGCATTGGT,IntFwd:ACGTTTCAGAAAGTAGGACC
Distributed lab
DepositorDr. S. Mitani
References Please submit your publication
Perez-Gomez A, Carretero M, Weber N, Peterka V, To A, Titova V, Solis G, Osborn O, Petrascheck M.
A phenotypic Caenorhabditis elegans screen identifies a selective suppressor of antipsychotic-induced hyperphagia.
Nat Commun 2018 9(1) 5272 
[ PubMed ID = 30532051 ] [ RRC reference ]

Vidal-Gadea A, Topper S, Young L, Crisp A, Kressin L, Elbel E, Maples T, Brauner M, Erbguth K, Axelrod A, Gottschalk A, Siegel D, Pierce-Shimomura JT.
Caenorhabditis elegans selects distinct crawling and swimming gaits via dopamine and serotonin.
Proc Natl Acad Sci U S A 2011 108(42) 17504-9 
[ PubMed ID = 21969584 ] [ RRC reference ]

Karmacharya R, Lynn SK, Demarco S, Ortiz A, Wang X, Lundy MY, Xie Z, Cohen BM, Miller GM, Buttner EA.
Behavioral effects of clozapine: involvement of trace amine pathways in C. elegans and M. musculus.
Brain Res 2011 1393 91-9 
[ PubMed ID = 21529784 ] [ RRC reference ]

Chase DL, Koelle MR.
Biogenic amine neurotransmitters in C. elegans.
WormBook 2007  1-15 
[ PubMed ID = 18050501 ] [ RRC reference ]