分離済み変異体

tm1034

Allele Name

tm1034

Balance

Not Required

OutCross

Not Accepted

Sequence Name

Y49E10.11

Gene Name

tat-1

Worm Base

Allele Name

tm1034

Gene Name

tat-1

Sequence

Y49E10.11

Phenotype

homozygous viable. Dr. M. Han: normal growth rate. Dr. S. Tuck: Traffick 10, 88 (2009).

Mutation site

47578/47579-A-48175/48176 (597 bp deletion + 1 bp insertion)

Chromosome

III

Putative gene structure

complement(join(31959..32056, 32642..32766, 37381..37473, 38318..38574, 39898..40038, 40248..40381, 40524..40678, 42286..42815, 44720..45258, 46349..46649, 47456..47568, 48159..48398, 50066..50372, 51442..51627, 52670..52769, 52820..52877, 53218..53260))

Map position

17.57

Balancer

Map position of balancer

Sequence of primers

ExtFwd:CCAGTATGACAAACAGCCAT,IntFwd:CACATTCCGTGTAAGAGTGC,ExtRev:CTACACTGGACACGACTCAA,IntRev:ACGACTCAAAGCTGCTCATG

Distributed lab

Depositor

Dr. S. Mitani

References

Please submit your publication

Raiders S, Black EC, Bae A, MacFarlane S, Klein M, Shaham S, Singhvi A.
Glia actively sculpt sensory neurons by controlled phagocytosis to tune animal behavior.
Elife 2021 10
[ PubMed ID = 33759761 ] [ RRC reference ]

Denning DP, Hatch V, Horvitz HR.
Both the caspase CSP-1 and a caspase-independent pathway promote programmed cell death in parallel to the canonical pathway for apoptosis in Caenorhabditis elegans.
PLoS Genet 2013 9(3) e1003341
[ PubMed ID = 23505386 ] [ RRC reference ]

Nawa M, Kage-Nakadai E, Aiso S, Okamoto K, Mitani S, Matsuoka M.
Reduced expression of BTBD10, an Akt activator, leads to motor neuron death.
Cell Death Differ 2012 19(8) 1398-407
[ PubMed ID = 22388351 ] [ RRC reference ]

Wang X, Li W, Zhao D, Liu B, Shi Y, Chen B, Yang H, Guo P, Geng X, Shang Z, Peden E, Kage-Nakadai E, Mitani S, Xue D.
Caenorhabditis elegans transthyretin-like protein TTR-52 mediates recognition of apoptotic cells by the CED-1 phagocyte receptor.
Nat Cell Biol 2010 12(7) 655-64
[ PubMed ID = 20526330 ] [ RRC reference ]

Seamen E, Blanchette JM, Han M.
P-type ATPase TAT-2 negatively regulates monomethyl branched-chain fatty acid mediated function in post-embryonic growth and development in C. elegans.
PLoS Genet 2009 5(8) e1000589
[ PubMed ID = 19662161 ] [ RRC reference ]

Ruaud AF, Nilsson L, Richard F, Larsen MK, Bessereau JL, Tuck S.
The C. elegans P4-ATPase TAT-1 regulates lysosome biogenesis and endocytosis.
Traffic 2009 10(1) 88-100
[ PubMed ID = 18939953 ] [ RRC reference ]

Darland-Ransom M, Wang X, Sun CL, Mapes J, Gengyo-Ando K, Mitani S, Xue D.
Role of C. elegans TAT-1 protein in maintaining plasma membrane phosphatidylserine asymmetry.
Science 2008 320(5875) 528-31
[ PubMed ID = 18436785 ] [ RRC reference ]