Home > 分離済み変異体 > tm1027

分離済み変異体

Allele Name		tm1027
Allele Type		通常株
Sequence Name		T06C12.10
Gene Name		cgt-1
Worm Base	Allele Name	tm1027
	Gene Name	cgt-1
	Sequence	T06C12.10
Phenotype Information from the receiver is posted in the form of a "researcher : phenotype"		homozygous viable
Mutation site Please see gene structure to locate the deletion in relation to exon(s)		21344/21345-22280/22281 (936 bp deletion)
Chromosome		V
Putative gene structure		complement(join(20129..20178, 20276..20438, 20735..21058, 21213..21433, 21480..21715, 21774..22005, 22058..22100))
Map position		9.1
Balancer
Map position of balancer
Sequence of primers		ExtFwd:CCCATTCCTAAAAACACTGC,IntRev:GATATTTCGTGCAGAAGCTC,ExtRev:ACAACTTCCTTCAGTCAGAG,IntFwd:GGATGTTTCCAAACTTTCGG
Distributed lab
Depositor		Dr. S. Mitani/NBRP
References		Please submit your publication Cui M, Wang Y, Cavaleri J, Kelson T, Teng Y, Han M. Starvation-Induced Stress Response Is Critically Impacted by Ceramide Levels in Caenorhabditis elegans. Genetics 2017 205(2) 775-785  [ PubMed ID = 27974500 ] [ RRC reference ] Boland S, Schmidt U, Zagoriy V, Sampaio JL, Fritsche RF, Czerwonka R, Lübken T, Reimann J, Penkov S, Knölker HJ, Kurzchalia TV. Phosphorylated glycosphingolipids essential for cholesterol mobilization in Caenorhabditis elegans. Nat Chem Biol 2017 13(6) 647-654  [ PubMed ID = 28369040 ] [ RRC reference ] Nomura KH, Murata D, Hayashi Y, Dejima K, Mizuguchi S, Kage-Nakadai E, Gengyo-Ando K, Mitani S, Hirabayashi Y, Ito M, Nomura K. Ceramide glucosyltransferase of the nematode Caenorhabditis elegans is involved in oocyte formation and in early embryonic cell division. Glycobiology 2011 21(6) 834-48  [ PubMed ID = 21325339 ] [ RRC reference ] Zhu H, Shen H, Sewell AK, Kniazeva M, Han M. A novel sphingolipid-TORC1 pathway critically promotes postembryonic development in Caenorhabditis elegans. Elife 2013 2 e00429  [ PubMed ID = 23705068 ] [ RRC reference ] Kniazeva M, Zhu H, Sewell AK, Han M. A Lipid-TORC1 Pathway Promotes Neuronal Development and Foraging Behavior under Both Fed and Fasted Conditions in C. elegans. Dev Cell 2015 33(3) 260-71  [ PubMed ID = 25892013 ] [ RRC reference ] Marza E, Simonsen KT, Faergeman NJ, Lesa GM. Expression of ceramide glucosyltransferases, which are essential for glycosphingolipid synthesis, is only required in a small subset of C. elegans cells. J Cell Sci 2009 122(Pt 6) 822-33  [ PubMed ID = 19240113 ] [ RRC reference ]